The eastern region, comprised by three counties located almost one over the other in northeast-southwest direction, Szabolcs-Szatmár, Hajdú-Bihar, and Szolnok, is bordered by the Romanian and Ukrainian borders from one side, and by the River Tisza from the other side. The monotony of its plains is disrupted by saliferous lakes surrounded by reeds, acacia trees to break the wind, and the blue ribbons of rivers flowing into the River Tisza.
Flourishing settlements were developed in the area after the conquest of the Magyars, devastated by the Mongol invasion in 1241, and blocking their development for several decades. The history of Nyí regyháza provides an appropriate example for this process. The Turks hardly managed or did not manage at all to invade the northern parts of the region, therefore many buildings from Árpád’s age and the Medieval Era were preserved in relatively good state. In the Romanesque church of Csaroda there are wall paintings dating back to the 13th century; the Medieval churches of Nyírbátor have been almost completely preserved. In the 16th century, the spread of Protestantism brought about changes in town life. Debrecen became not only the fortress of Calvinism but a cultural centre as well for a long time. The Vay Palace of Vaja provides a nice example of 17-18th century palaces for the aristocracy.
The protected habitats of Hortobágy National Park and Körös-Maros National Park preserve a unique flora and fauna. In the area of Csaroda and Bátoliget, the remnants of the ancient peat moss marsh are still observable. It used to be characteristic of the Bereg area, with some pre-glacial plant and animal species. There are huge ancient trees in the nature park of Tiszakürt. The plants of the already more famous Szarvas nature park originate from here.
There are many relics of the characteristic folk architecture and folk traditions. The church of Tákos and the belfry of Nyírbátor Reformed Church are beautiful examples for church ceilings of painted wood panels and wooden bell belfries characteristic of the Nyírség area. The water mill in Túristvándi is a monument of industrial history. In the open-air museum of Nyíregyháza you can find residential houses characteristic of the region. The graveyard of Szatmá rcseke is extremely interesting. This is the only place where boat-formed, human-faced grave-posts can be observed. Máriapó cs is one of the major places of pilgrimage in Hungary. Several tens of thousand people go on pilgrimage there to the picture titled “Weeping Madonna”- considered to be miraculous.
Rowing tours start from the Upper Tisza region all over the summer; in Szolnok there are even rowing camps in the summer. Motor watersports can be enjoyed on Lake Tisza.
The region is extremely rich in medicinal waters. Hajdúszoboszló is famous internationally, but many people visit to the spas of Nyíregyháza-Sóstó, Debrecen, and Szolnok as well.